2014年9月28日星期日

The five stages of diabetic nephropathy

Any disease produces are periodic, different stages have different treatment at the same time, not any stage of the disease is to use the same method of treatment. Let's look at the five stages of the disease of diabetic nephropathy is what kind of, respectively, for the treatment of patients in the future to do the reference. Diabetic nephropathy is one of the chronic complications of diabetes,Below is the pathogenesis of diabetic nephropathy five stages.
First, patients with diabetic nephropathy, renal blood flow and glomerular capillary perfusion and internal pressure were increased, there is no damage and clinical symptoms histopathology.
Second, patients with diabetic nephropathy, there is no obvious clinical symptoms, so treatment at this time is the best stage.
Third, there will be a continuous trace albuminuria in patients with moderately elevated blood pressure in patients with this issue, part of the lower blood pressure can reduce the urine trace albumin excretion.
The fourth, for clinical diabetic nephropathy period, this period is characterized by a large number of albuminuria, may be accompanied by hypertension, edema, and even nephrotic syndrome "appearance, normal or slightly decreased glomerular filtration rate. For intervention treatment of this period, can reverse and not slow down the progress of renal failure, but if not treated, will gradually decline in renal function, if accompanied by hypertension, or smoking, decline in renal function will be faster.
Five, is ESRD, also known as uremia, generally occurs in 20 to 40 years after the onset of diabetes. This issue of diabetic kidney disease, because of its extensive glomerular basement membrane thickening of the glomerular capillary lumen stenosis and more progressive glomerular deserted, kidney filtration
Function decreased, leading to kidney failure. Also secondary uremic neuropathy and cardiomyopathy. These serious complications in uremic patients with diabetic nephropathy is often the cause of death.

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