Clinical manifestations of diabetic nephropathy:
1, proteinuria: no clinical proteinuria early diabetic nephropathy, only by radioimmunoassay method to detect microalbuminuria. The only early clinical manifestations of diabetic nephropathy proteinuria, proteinuria gradually evolved from intermittent to continuous.
2, edema: early clinical diabetic nephropathy generally do not have edema, a few patients before plasma protein decreased, may have mild edema. If a large number of proteinuria, plasma proteins is low, edema, progression to advanced performance, mostly.
3, high blood pressure: in type 1 diabetic patients without nephropathy prevalence of hypertension than normal does not increase, type 2 diabetic patients with hypertension more, but if the proportion of elevated blood pressure proteinuria in there nephrotic syndrome patients with hypertension, the most moderate hypertension, a few severe.
4, renal failure: a great difference in the speed of progression of diabetic nephropathy. Some patients with mild proteinuria sustainable for many years, but with normal renal function, urinary protein rarely some patients can quickly develop nephrotic syndrome, renal function gradually deteriorated, culminating in uremia.
5, anemia; diabetic nephropathy in patients with significant azotemia, may have mild to moderate anemia. Anemia is erythropoietin disorders, iron therapy ineffective.
6, the performance of cardiovascular disease complications in other organs such as heart failure, myocardial infarction. Neuropathy, such as peripheral neuropathy. Neurogenic bladder can occur when involving the autonomic nervous. Retinopathy, diabetic nephropathy severe diabetic retinopathy is almost 100%, but there are severe retinopathy may not have significant kidney disease. When the progress of diabetic nephropathy, retinopathy often accelerated deterioration.
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